Person

Wenjing Xu

M. Sc.

PhD Student

Research Area Functional and Interactive Polymers and DWI - Leibniz Institute for Interactive Materials e.V.

Address

Building:  5391/ Bestandsbau

Room: A 3.04

DWI - Leibniz Institute for Interactive Materials e.V.

Forckenbeckstraße 50

52056 Aachen

Contact

WorkPhone
Phone: +49 241 80 23388
  Wenjing Xu Research Copyright: Wenjing Xu

Overview on Research

The aim of my research is to synthesize novel polyampholyte microgels with controlled distribution of ionizable groups. To achieve this goal new synthesis routes were developed to synthesize polyampholyte microgels with controlled chemical structure, morphology and distribution of ionizable groups (Statistical, Core-shell and Janus-like). The synthesized polyampholyte microgel systems are stimuli responsive, biocompatible and biodegradable, thus are interesting candidates as carrier systems for biomolecules such as as protein and peptides for application in medicine and agricultural technologies.

Research focus

  • Synthesis and characterization of responsive microgels
  • Application of microgels as carrier systems for proteins and peptides
  • Fabrication of colloidal superstructures

Projects

SFB 985 A3: Amphoteric microgels for uptake and release of polyelectrolytes
BioSC: Green Release

Publications

W. Xu, A. Rudov, A. Oppermann, S. Wypysek, M. Kather, R. Schroeder, W. Richtering, I. I. Potemkin, D. Wöll, A. Pich; Synthesis of Polyampholyte Microgels by Precipitation Polymerization; Angew.Chem. Int. Ed.; 2020; 59, 1248-1255.

W. Xu, A. A. Rudov, S. Schroeder, I. V. Portnov, W. Richtering, I. I. Potemkin, A. Pich; Distribution of Ionizable Groups in Polyampholyte Microgels Controls Interactions with Captured Proteins: From Blockade and "Levitation" to Accelerated Release; Biomacromolecules; 2019; 20, 4, 1578-1591.

R. A. Gumerov1, E. Gau1, W. Xu1, A. Melle, S. A. Filippov, A. S. Sorokina, N. A. Wolter, A. Pich, I. I. Potemkin; Amphiphilic PVCL/TBCHA microgels: From synthesis to characterization in a highly selective solvent; J. Colloid Interface Sci.; 2020, 564, 334-356.

H. Peng, W. Xu, A. Pich; Temperature and pH dual-responsive poly(vinyl lactam) copolymers functionalized with amine side groups via RAFT polymerization; Polym. Chem.; 2016; 7, 5011-5022.

K.H. Tan, W. Xu, S. Stefka, D. E. Demco, T. Kharandiuk, V. Ivasiv, R. Nebesnyi, V. S. Petrovskii, I. I. Potemkin, A. Pich; Selenium-Modified Microgels as Bio-Inspired Oxidation Catalysts; Angew. Chem., Int. Ed.; 2020; 58, 9791-9796.

M. A. S. Mertens, F. Thomas, M. Nöth, J. Moegling, I. El-Awaad, D. F. Sauer, G. V. Dhoke, W. Xu, A. Pich, S. Herres-Pawlis, U. Schwaneberg; One-Pot Two-Step Chemoenzymatic Cascade for the Synthesis of a Bis-benzofuran Derivative; Eur. J. Org. Chem.; 2019, 6341–6346.