Agnieszka Ksiazkiewicz

M. Sc.

PhD Student

Research Area Functional and Interactive Polymers and DWI - Leibniz Institute for Interactive Materials e.V.


Building:  5393/ Erweiterungsbau

Room: B 3.56

DWI - Leibniz Institute for Interactive Materials e.V.

Forckenbeckstraße 50

52056 Aachen


Phone: +49 241 80 23183
  Agnieszka Ksiazkiewicz Research Copyright: Agnieszka Ksiazkiewicz

Overview on Research

My research focuses on the investigation of polymerization kinetics and microgel formation mechanisms during precipitation polymerization reactions by experimental approaches. The combination of on-line analytics like reaction calorimetry, DLS or Raman spectroscopy allows for monitoring of the microgel synthesis in-situ and helps to understand the reaction mechanisms. Such detailed analysis of the reactions permits the generation of computational models helping to predict experimental recipes in order to produce special morphologies, cross-link densities or sizes of microgels. The batch reactions are optimized and compared to syntheses in continuous flow.

Research focus

  • Synthesis and characterization of responsive microgels
  • On-line analytics used for process monitoring
  • Polymerization in continuous flow


SFB 985 B4: Microgel synthesis: Kinetics, particle formation and reactor modelling


A. N. Ksiazkiewicz, L. Bering, F. Jung, N. A. Wolter, J. Viell, A. Mitsos, A. Pich; Closing the 1-5 µm Size Gap: Temperature‑programmed, Fed-batch Synthesis of µm-sized Microgels; Chemical Engineering Journal, 2019, 379, 122293.

R. D. Rittinghaus, J. Tremmel, A. Ruzicka, C. Conrads, P. Albrecht, A. Hoffmann, A. N. Ksiazkiewicz, A. Pich, R. Jambor, S. Herres-Pawlis; Undiscovered Potential: Ge Catalysts for Lactide Polymerization; Chemistry: A European Journal, 2019, 25, 1–11.

M. Fuchs, S. Schmitz, P. M. Schäfer, T. Secker, A. Metz, A. N. Ksiazkiewicz, A. Pich, P. Kögerler, K. Y. Monakhov, S. Herres-Pawlis; Mononuclear zinc(II) Schiff base complexes as catalysts for the ring-opening polymerization of lactide; European Polymer Journal, 2019, 109302.

F. A. L. Janssen, M. Kather, A. Ksiazkiewicz, A. Pich, A. Mitsos; Synthesis of Poly(N-vinylcaprolactam)-Based Microgels by Precipitation Polymerization: Pseudo-Bulk Model for Particle Growth and Size Distribution; ACS Omega, 2019, 4, 9, 13795-13807.

D. Ghosh, P. M. Schäfer, D. Dittrich, C. Scheiper, P. Steiniger, G. Fink, A. N. Ksiazkiewicz, A. Tjaberings, C. Wölper, A. H. Gröschel, A. Pich, S. Herres-Pawlis, S. Schulz; Heterolepic β ‐Ketoiminate Zinc Phenoxide Complexes as Efficient Catalysts for the Ring Opening Polymerization of Lactide; ChemistryOpen, 2019, 8, 951 – 960.

F. Jung, A. Ksiazkiewicz, A. Mhamdi, A. Pich, A. Mitsos; Model-based prediction of the hydrodynamic radius of collapsed microgels and experimental validation; Chemical Engineering Journal, 2019, 378, 121740.

R. D. Ruttinghaus, P. M. Schäfer, P. Albrecht, C. Conrads, A. Hoffmann, A. N. Ksiazkiewicz, O. Bienemann, A. Pich, S. Herres-Pawlis; New Kids in Lactide Polymerization: Highly Active and Robust Iron Guanidine Complexes as Superior Catalysts; ChemSusChem – Chemistry & Sustainability, 2019, 12, 2161-2165.

F. Jung, F.A. L. Janssen, A. Ksiazkiewicz, A. Caspari, A. Mhamdi, A. Pich, A. Mitsos; Identifiability Analysis and Parameter Estimation of Microgel Synthesis: A Set-Membership Approach; Industrial & Engineering Chemistry Research, 2019, 58, 30, 13675-13685.

P. M. Schäfer, P. McKeown, M. Fuchs, R. D. Rittinghaus, A. Hermann, J. Henkel, S. Seidel, C. Roitzheim, A. N. Ksiazkiewicz, A. Hoffmann, A. Pich, M. D. Jones, S. Herres-Pawlis; Tuning a robust system: N,O zinc guanidine catalysts for the ROP of lactide; Dalton Transactions, 2019, 48, 6071.

F. A. L. Janssen, A. Ksiazkiewicz, M. Kather, L. C. Kröger, A. Mhamdi, K. Leonhard, A. Pich, A. Mitsos; Kinetic Modeling of Precipitation Terpolymerization for Functional Microgels; Computer Aided Chemical Engineering, 2018, 43, 109-114.

P. Steiniger, P. M. Schäfer, C. Wölper, J. Henkel, A. N. Ksiazkiewicz, A. Pich, S. Herres-Pawlis, S. Schulz; Synthesis, Structures, and Catalytic Activity of Homo‐ and Heteroleptic Ketoiminate Zinc Complexes in Lactide Polymerization; European Journal of Inorganic Chemistry, 2018, 4014–402.

J. Meyer-Kirschner, M. Kather, A. Ksiazkiewicz, A. Pich, A. Mitsos, J. Viell; Monitoring Microgel Synthesis by Copolymerization of N‐isopropylacrylamide and N‐vinylcaprolactam via In‐Line Raman Spectroscopy and Indirect Hard Modeling; Macromolecular Reaction Engineering, 2018, 12, 1700067.

E. Gau, F. Flecken, A. N. Ksiazkiewicz, A. Pich; Enzymatic synthesis of temperature-responsive poly(N-vinylcaprolactam) microgels with glucose oxidase; Green Chemistry, 2018, 20, 431.